Structure cristalline de la L-leucyl-L-leucyl-L-tyrosine chlorhydraté

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Crystal structure of l-leucyl-l-isoleucine 2,2,2-tri­fluoro­ethanol monosolvate

Hydro-phobic dipeptides with either l-Leu or l-Phe constitute a rather heterogeneous group of crystal structures. Some form materials with large water-filled channels, but there is also a pronounced tendency to incorporate organic solvent mol-ecules, which then act as acceptors for one of the three H atoms of the charged N-terminal amino group. l-Leu-l-Ile has uniquely been obtained as two dist...

متن کامل

Standard Thermodynamic Functions of Tripeptides N-Formyl-l-methionyl-l-leucyl-l-phenylalaninol and N-Formyl-l-methionyl-l-leucyl-l-phenylalanine Methyl Ester

The heat capacities of tripeptides N-formyl-l-methionyl-l-leucyl-l-phenylalaninol (N-f-MLF-OH) and N-formyl-l-methionyl-l-leucyl-l-phenylalanine methyl ester (N-f-MLF-OMe) were measured by precision adiabatic vacuum calorimetry over the temperature range from T = (6 to 350) K. The tripeptides were stable over this temperature range, and no phase change, transformation, association, or thermal d...

متن کامل

N-Methyl-l-leucyl-l-leucine hydro­chloride monohydrate

In the title compound C(13)H(27)N(2)O(3) (+)·Cl(-)·H(2)O, obtained by deprotecting the amino and carboxyl groups of an inter-mediate in the synthesis of the cyclic penta-peptide Galaxamide, a number of hydrogen-bonding inter-actions occur including aminium N-H⋯Cl, amide-carboxyl N-H⋯O, water O-H⋯Cl and carbox-yl-water O-H⋯O associations. The aminium N-H⋯Cl⋯H-N bridging extensions give rise to z...

متن کامل

Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling

BACKGROUND Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal (MG132), a peptide aldehyde proteasome inhibitor, can inhibit tumor progression by inactivating nuclear factor (NF)-κB signaling. Paclitaxel (PTX) is part of a routine regimen for the treatment of breast cancer. However, activation of the NF-κB pathway after treatment with PTX confers insensitivity to this drug. This study investigated the po...

متن کامل

Production of acetyl-L-leucyl-L-argininal, inhibitor of dipeptidyl aminopeptidase III by bacteria.

Sir: As part of our continuous effort toward the discovery of novel enzyme inhibitors from microbial cultures1~3), we have searched for inhibitors against dipeptidyl aminopeptidases. We wish to report the discovery of acetyl-L-leucyl-L-argininal as a specific inhibitor against dipeptidyl aminopeptidase III (DAP-III, EC 3.4.14.4) from the culture filtrate of a bacterium (BMG520-yF2). Although th...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Acta Crystallographica Section C Crystal Structure Communications

سال: 1988

ISSN: 0108-2701

DOI: 10.1107/s0108270188000940